dump date 20110803_095409 -- class Genbank::Feature
Glykogensyntaskinas-3 beta Svensk MeSH
Glycogen synthase kinase-3 beta (GSK3B) was named due to its ability to phosphorylate and inactivate glycogen synthase. GSK3B is a multifunctional serine/threonine kinase which has been implicated in multiple biological processes including embryonic development, cell differentiation, apoptosis and insulin response. Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease. Akt/GSK-3 cascade is one of the signaling pathways that is involved in dopamine D2 receptor mediated effects, as it has been reported that in mice lacking GSK-3, the striatal function of D2 receptor is impaired (111).
on Tue Oct 22 12:49:34 UTC 2019 GSK3B - Glycogen Synthase Kinase-3 Beta. Looking for abbreviations of GSK3B? It is Glycogen Synthase Kinase-3 Beta. Glycogen Synthase Kinase-3 Beta listed as GSK3B. GSK3B A gene on chromosome 3q13.3 that encodes a serine-threonine kinase of the glycogen synthase kinase subfamily, which is involved in glycogen metabolism, proliferation, motility, survival, neuronal development and body pattern formation. View application images and datasheets for 981 anti Glycogen-Synthase-Kinase-3-Beta Antibody antibodies from 37 leading antibody suppliers, plus reviews and the top related antibodies Lithium Chloride Promotes Apoptosis in Human Leukemia NB4 Cells by Inhibiting Glycogen Synthase Kinase-3 Beta .
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Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Glycogen synthase kinase-3 beta (GSK3B) was named due to its ability to phosphorylate and inactivate glycogen synthase.
115641 20832 1065 01096nam a2200277 4500 oai:gup.ub
Det är vanligt att föräldrar vill veta mer om ärftlighet vid psykiatriska diagnoser. 4. glycogen synthase kinase 3-beta (GSK3b). This ECG pattern is present in 3-13% of the general population. of the Akt-glycogen synthase kinase 3 beta signalling pathway together with phosphorylation 3 Genetiskt sjukdomspanorama Kromosomavvikelser 4/1000 Monogena sjukdomar 50/1000 Komplexa 12 glycogen synthase kinase 3-beta (GSK3b). Antalet celler i S-fasen var 44, 6 ± 3, 6% i obehandlade celler och minskade till 18, Fosforyleringsnivåer av PKB vid Ser473 och fosforyleringsnivåer av GSK3- ß signal-regulated protein kinase 1/2.
Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that specific serine residues Ser21 and Ser9 in GSK-3 isoforms α and β, respectively. May 30, 2019 Three of the other associated genes in this study also interact with the Wnt signaling pathway upstream and downstream of glycogen synthase
A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved
EC 2.7.1.37. Engelsk definition. A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse
GSK3-β eller glykogensyntas-kinas 3 beta är ett enzym som kodas av GSK3β-genen. Det är involverat i intracellulär signalering genom att påverka metabolism,
ELISA Kit for Glycogen Synthase Kinase 3 Beta (GSK3b).
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reticulum stress and IκB kinase β/nuclear factor-κB-mediated inflammatory pathways in mice. av N Knuutinen · 2020 — synthase kinase 3, GSK3) och kaseinkinas 1 (eng.
GSK3beta is a Ser/Thr protein kinase, and there is emerging evidence that it is a tumor suppressor in oral cancer. 2015-07-01 · Glycogen synthase kinase 3 beta (GSK-3β), one of the GSK-3 isomers, plays a major role in neuronal apoptosis and its inhibition decreases expression of alpha-Synuclein (α-Synuclein), which make this kinase an attractive therapeutic target for neurodegenerative disorders.
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GSK3B – Wikipedia
Glycogen synthase kinase 3 β (GSK3β) is an enzyme involved in the suppression of tumor progression, as it downregulates oncogenic pathways such as the Wnt signaling and the cyclin D1 activation. RKIP was found to bind to GSK3β and maintains the protein in its active form. Recent developments suggest an active role of glycogen synthase kinase 3 beta (GSK3 beta) in various human cancers either as a tumor suppressor or as a tumor promoter.